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Re2O
“Adding Skin to Skin”. A next-generation skin booster that directly replenishes human-derived ECM components, helping rebuild and restore the skin from its very foundation.
Treatment time
20–30 minutes
Recovery period
Immediate return to daily activities
Duration of effect
Results last 1 to 1.5 years after completing the full session

Massage the treated area gently after the procedure

Right after the procedure, the medical staff will softly massage the treated area to help the particles spread evenly. At home, light massage may also be recommended.

Possible swelling & bruising

As with any injection, mild swelling or bruising may occur, but this usually subsides within 24–48 hours.

Avoid irritating environments

For one week after treatment, avoid saunas, hot baths, and excessive exercise.

Sun protection & hydration

When going outdoors, apply sunscreen thoroughly, and keep your skin well-moisturized to prevent dryness.

Is the “allogeneic dermis” used in Re2O really safe?

Yes. Only acellular human-derived dermis (hADM) is used, where all cells that could trigger an immune response have been removed. With the patented AlloClean™ technology, residual DNA is minimized, meeting the U.S. FDA’s raw material standards and approved by the Korean MFDS, making it an extremely safe ingredient.

What is the biggest difference compared to other collagen boosters (e.g., Rejuran, Juvelook)?

While traditional skin boosters mainly stimulate skin cells to induce collagen production, Re2O works by directly replenishing the extracellular matrix (ECM)—the skin’s core structure. Like rebuilding the foundation of a house, it offers more fundamental improvements in skin condition and elasticity restoration.

When do the results appear?

Re2O works in two phases. Immediately after the procedure, the injected ECM components create subtle volume, instantly improving skin texture. Over the following weeks, fibroblasts are stimulated to generate new collagen, elastin, and hyaluronic acid. Clinical studies confirmed significant improvements in pores, elasticity, texture, and redness as early as 4 weeks post-treatment.

RE2O

Re2O is a skin booster made from micro-particles of human-derived dermis that have been safely processed for medical use. By directly replenishing the extracellular matrix (ECM) — the skin’s essential components such as collagen and elastin — it helps rebuild the skin’s fundamental structure and creates a healthier skin environment. This next-generation regenerative solution strengthens the skin’s own ability to recover, improving multiple concerns at once, including elasticity, fine lines, pores, and hydration.

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SPECIALITYTreatment Highlights
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The End of Imitation—Adding Real Skin

Not artificial stimulation, but direct replenishment with ECM components identical to your skin's own structure

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From Pores to Redness, All Concerns at Once

Clinically proven to improve pores, elasticity, skin texture, and redness with comprehensive results

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Skin That Looks Younger With Time

By restoring the skin's fundamental environment, it helps maintain healthy, youthful skin for longer

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RECOMMENDED FORWho It Is For

For those with thin, sagging skin who want fundamental improvement

For those struggling with enlarged pores, fine lines, and rough texture

For those who prefer safe, biocompatible treatments over artificial ingredients

For those seeking natural anti-aging by restoring a healthy skin foundation

TREATMENT AREASWhere It Is For
Crow's Feet 프로필

Crow's Feet

DERNA PROCESSUnique DERNA Process
Identifying Concerns
STEP 1. 3D Precision Skin AnalysisIdentifying Concerns
Using AI-based diagnostic equipment, we scientifically analyze skin thickness, moisture and oil balance, fine lines, pores, and other underlying issues.
Creating the Optimal Plan
STEP 2. Personalized 1:1 Treatment DesignCreating the Optimal Plan
Based on the diagnostic data and medical evaluation, we design the most effective injection points, depth, and dosage tailored to each individual’s skin condition.
Precise & Safe Procedure
STEP 3.Precise & Safe Procedure
Following the customized plan, skilled medical professionals perform the treatment with refined techniques, minimizing product loss and ensuring the active ingredients are accurately delivered into the dermis.
SPECIAL PAIN CAREPain Management System
SPECIAL PAIN CARE
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Highly Concentrated Numbing Cream

Beyond simple application, a specialized wrapping enhances absorption, allowing the numbing agents to penetrate deeply and effectively block surface pain.

RECOMMENDATIONSynergistic Treatments
DERNA
Re2O Effects? AI Skin Analysis ‘DERNA Clinic’