

Massage the treated area gently after the procedure
Right after the procedure, the medical staff will softly massage the treated area to help the particles spread evenly. At home, light massage may also be recommended.
Possible swelling & bruising
As with any injection, mild swelling or bruising may occur, but this usually subsides within 24–48 hours.
Avoid irritating environments
For one week after treatment, avoid saunas, hot baths, and excessive exercise.
Sun protection & hydration
When going outdoors, apply sunscreen thoroughly, and keep your skin well-moisturized to prevent dryness.
Is the “allogeneic dermis” used in Re2O really safe?
Yes. Only acellular human-derived dermis (hADM) is used, where all cells that could trigger an immune response have been removed. With the patented AlloClean™ technology, residual DNA is minimized, meeting the U.S. FDA’s raw material standards and approved by the Korean MFDS, making it an extremely safe ingredient.
What is the biggest difference compared to other collagen boosters (e.g., Rejuran, Juvelook)?
While traditional skin boosters mainly stimulate skin cells to induce collagen production, Re2O works by directly replenishing the extracellular matrix (ECM)—the skin’s core structure. Like rebuilding the foundation of a house, it offers more fundamental improvements in skin condition and elasticity restoration.
When do the results appear?
Re2O works in two phases. Immediately after the procedure, the injected ECM components create subtle volume, instantly improving skin texture. Over the following weeks, fibroblasts are stimulated to generate new collagen, elastin, and hyaluronic acid. Clinical studies confirmed significant improvements in pores, elasticity, texture, and redness as early as 4 weeks post-treatment.

Re2O is a skin booster made from micro-particles of human-derived dermis that have been safely processed for medical use. By directly replenishing the extracellular matrix (ECM) — the skin’s essential components such as collagen and elastin — it helps rebuild the skin’s fundamental structure and creates a healthier skin environment. This next-generation regenerative solution strengthens the skin’s own ability to recover, improving multiple concerns at once, including elasticity, fine lines, pores, and hydration.



Not artificial stimulation, but direct replenishment with ECM components identical to your skin's own structure


Clinically proven to improve pores, elasticity, skin texture, and redness with comprehensive results


By restoring the skin's fundamental environment, it helps maintain healthy, youthful skin for longer


For those with thin, sagging skin who want fundamental improvement
For those struggling with enlarged pores, fine lines, and rough texture
For those who prefer safe, biocompatible treatments over artificial ingredients
For those seeking natural anti-aging by restoring a healthy skin foundation


Crow's Feet








Beyond simple application, a specialized wrapping enhances absorption, allowing the numbing agents to penetrate deeply and effectively block surface pain.