What symptoms appear if Botox resistance develops?

The most representative signals are reduced effectiveness and shortened maintenance periods. Effects that previously lasted about 4 to 6 months may noticeably shorten (e.g., less than 4 months), or even with the same dosage, the movement of facial muscles may not decrease as much as before. However, it is important to check whether the same pattern repeats consecutively more than twice before concluding that resistance has developed.