Q&A
Answered2026.08.10

After multiple treatments, it seems like the effects are not as strong as before. Have I developed a tolerance to Botox?

After multiple treatments, it seems like the effects are not as strong as before. Have I developed a tolerance to Botox?

Derna

2026.08.10

Repeatedly receiving high doses at short intervals can lead to the formation of neutralizing antibodies in the body, reducing effectiveness and creating tolerance. If you are concerned about tolerance, switching to products like Xeomin or Coretox with lower complex protein content may be a solution.

DERNA