What are the effects of CellREDM? Improvements in skin texture, pores, and fine lines
2026-08-24
CellREDM is a 5th generation skin booster made from human-derived acellular dermal matrix (hADM) components that complements the extracellular matrix (ECM) environment itself.
With the effects of CellREDM, improvements in skin texture, dryness, pores, fine lines, and density can be expected.
It is generally recommended to undergo 3 intensive treatments at 4-week intervals, followed by maintenance treatments every 6 months to 1 year (individual variations may apply).
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Even though they are the same skin boosters, why do people feel different effects? Ultimately, it is because the materials that create collagen and the physical strength to produce it vary from person to person. Therefore, recently, skin boosters that directly fill in the necessary components instead of inducing collagen production have been gaining attention. Today, we will take a look at one of them, CellREDM.
What is CellREDM? Characteristics of hADM components and ECM
Skin aging cannot be simply explained by a lack of moisture. Changes in skin texture, elasticity, and density can occur as the structure supporting the skin weakens. The ECM (extracellular matrix) plays a crucial role in this process. The ECM is the environment that supports skin cells, composed of various components related to skin structure, such as collagen and elastin.
CellREDM is a skin booster based on human-derived acellular dermal matrix, or hADM. It is characterized by utilizing ECM components related to skin structure after removing cellular components. Therefore, it can be understood from the perspective of complementing the environment that supports the skin rather than simply focusing on stimulating skin cells.
What are the effects of CellREDM? What changes can be expected in skin texture, pores, and fine lines?
The effects of CellREDM are meaningful in that they aim for overall improvement in skin condition while complementing the environment that supports the skin, rather than focusing on improving just one skin concern.
1️⃣ Improvement in Skin Texture
As the internal environment of the skin is organized, the rough and dull skin texture may feel smoother. If you have been troubled by makeup settling into your skin, you can expect changes in the surface of your skin becoming more organized.
2️⃣ Relief of Internal Dryness
When the skin is dry, not only does the visible skin texture become more pronounced, but fine lines can also appear more prominent. CellREDM can help alleviate internal dryness and maintain a feeling of moisture through overall improvement of the skin environment.
3️⃣ Change in Pores Appearing Less Prominent
Due to decreased skin elasticity and density, pores may appear enlarged. By complementing the environment that supports the skin, if the skin has a firmer impression, you can expect changes where enlarged pores become less noticeable.
4️⃣ Reduction of Fine Lines
Especially fine lines that become more pronounced due to dryness or changes in skin texture can vary depending on skin condition. As skin texture and moisture levels become more organized, it can help fine lines appear smoother.
5️⃣ Improvement in Skin Density and Elasticity
Another change that can be expected from the effects of CellREDM is the overall skin density. When the skin feels thin and weak or appears to lack elasticity, complementing the environment that supports the skin can help create a firmer impression.
However, the effects of CellREDM do not manifest the same way in everyone. The changes felt and the number of treatments required can vary depending on the current skin condition, skin thickness, age, lifestyle, and management methods.
What is the treatment cycle for CellREDM? How many sessions should I receive?
CellREDM is generally recommended to undergo 3 intensive treatments at 4-week intervals, considering the skin regeneration cycle. After that, depending on the skin condition and maintenance level, maintenance treatments are often planned every 6 months to 1 year.
Immediately after the treatment, you may not notice significant changes. Typically, after 2 to 3 weeks, the skin texture becomes organized, and feelings of moisture or firmness gradually appear. However, the timing and degree of changes can vary from person to person, and it is important to remember that a single treatment does not uniformly improve all skin concerns.
Frequently Asked Questions
Q. How much does a single treatment (or 1 vial) of CellREDM cost?
The price of CellREDM varies depending on the hospital and ongoing events. For a single session, it typically ranges from 400,000 to 800,000 won. However, the amount may vary based on the treatment area, dosage (cc), and injection method (manual injection or injector), so it is best to confirm the exact cost through consultation.
Derna Clinic offers various skin booster events. Please check the exact prices on the event page below.
※ Events may change or end without notice. If you cannot find what you are looking for, please inquire for detailed guidance.
Q. How does the 'direct ECM supplementation' method differ from existing skin boosters like Rejuran or Juvelook?
Rejuran (PDRN) and Juvelook (PCL) stimulate fibroblasts to gradually induce collagen production. In contrast, CellREDM directly fills the dermal layer with ECM components such as collagen and elastin through the hADM (human-derived acellular dermal matrix) component.
Q. What are the differences between Litwo, which is also in the hADM category, and CellREDM?
Both products inject hADM-based collagen directly, but there is a slight difference in particle size: CellREDM is below 75㎛, while Litwo (RE2O) is below 100㎛. Many believe that the effects and durability are similar, so it is advisable to choose based on your skin condition and the clinic's experience. If you are curious about which product suits you better, consult with Derna Clinic.
Q. Is it as painful as Rejuran, to the point of tears? They say the ultra-fine particles cause less pain; how does it actually feel?
CellREDM is made of ultra-fine particles at the level of 75㎛, which generally results in less resistance during injection compared to coarser products. However, since it is an injection directly into the dermal layer, some degree of sting may be experienced. Pain perception varies greatly among individuals, so if you are sensitive to pain or in sensitive areas, it may help to allow sufficient time for the application of numbing cream.
Q. Is the embossing effect noticeable immediately after the treatment? Can I return to daily life right away?
Due to the characteristics of ultra-fine particles, the embossing effect is relatively minimal and tends to subside quickly. There may be slight swelling or redness immediately after the treatment, but most recover naturally within 1 to 3 days. Some clinics may allow washing and makeup on the same day, but for safety, it is recommended to wait until the next day.
Q. Which method is more effective: manual injection by a doctor or using equipment (injector/mirajet)?
Injectors can help distribute the medication evenly at a consistent pressure, while manual injections allow for fine adjustments by area. However, what is more important than the method itself is the skill of the practitioner in evenly injecting into the dermal layer, so it is advisable to check this aspect as well.
Q. Is it normal to see no changes for a few days after the treatment? When will I start to feel my skin becoming firmer?
It is common not to see noticeable changes immediately after the treatment, which can be considered a normal response. Typically, after 2 to 3 weeks, the skin texture becomes organized, and feelings of moisture or firmness gradually begin to appear. After about 4 weeks, changes in skin density and elasticity are often more distinctly felt, but the timing and degree of changes can vary among individuals.
Q. Since it is made from human-derived components, is there a risk of immune side effects like nodules (lumps) or allergies?
CellREDM is designed to reduce the risk of immune rejection by using acellular dermal matrix (hADM) from which cellular components have been removed. The ultra-fine particle formulation has a relatively low possibility of nodules forming, but initial immune reactions may occur rarely. If any adverse reactions persist, it is important to contact the clinic where you received the treatment immediately.
Q. How long do the effects last after completing the recommended number of sessions (3)? How often should I receive maintenance treatments afterward?
When the recommended 3 sessions are completed, the effects generally last for about a year. After the 3 sessions, continuing maintenance treatments every 6 months to 1 year can help sustain the improved condition. However, the maintenance period can vary depending on individual aging rates and lifestyle habits, so it is best to determine an accurate plan through consultation.
CellREDM focuses on complementing the ECM environment that supports the skin rather than providing immediate volume. However, even with the same ingredients, the results can vary depending on how uniformly they are injected into the dermal layer.
Therefore, it is important to receive an accurate diagnosis and design from experienced medical professionals, as well as to select the right ingredients. At Derna Clinic, we first assess the current skin condition and then conduct consultations considering the necessary number of sessions and injection methods.
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